Readings

The required textbook for this course is: Buy at Amazon Lodish, et al. Molecular Cell Biology. 5th ed. New York, NY: W.H. Freeman and Company, 2003. ISBN: 9780716743668.

SES # TOPICS READINGS
L1 Road map of course, what is and what is not cell biology, properties and behaviors of cells pp. 86-97, 184-193, and 235-239
L2 Structure of biological membranes, lipids and lipid modification, membrane proteins pp. 43-46, 147-152, 157-165, 182-184, 245-257, and 260-270
L3 Pumps, channels, transporters pp. 271-276
L4 Receptors, basics of signal transduction (Note: Reprise and extension in lecture 14) pp. 82-86, 533-556, 561-567, and 571-598
L5 Protein secretion, biogenesis of membrane proteins pp. 657-672 and 678-680
E1 Exam I (lectures 1-5)
L6 Regulation of the cell division cycle pp. 853-863 and 881-886
L7 Regulation of DNA replication pp. 874-881
L8 The microtubule cytoskeleton pp. 817-827 and 838-848
L9 Regulation of mitosis pp. 864-874
L10 Meiosis pp. 890-894
L11 Cell cycle checkpoints pp. 886-890
E2 Exam II (lectures 6-11)
L12 Protein modifications and intracellular transport, glycosylation, vesicular transport, receptor mediated endocytosis, lysosomes, organelle biogenesis pp. 165-173, 438-443, 509-513, 673-696, and 701-732
L13 Protein modifications and intracellular transport II pp. 165-173, 438-443, 509-513, 673-696, and 701-732
L14 Signal transduction: Detailed molecular mechanisms pp. 482-484 and 639-644
L15 Nerve cells, ion channels, synapse, Ca++ regulated events pp. 276-287
L16 Nerve cells II pp. 287-296 and 735-739
L17 Immunity and host pathogen interactions I Chapter 26, 6th ed. Provided as handout
L18 Immunity and host pathogen interactions II Chapter 26, 6th ed. Provided as handout
E3 Exam III (lectures 12-18)
L19 The actin-myosin cytoskeleton pp. 779-782, 784-786, 789-794, and 796-800
L20 The extracellular matrix pp. 197-209, 223-227, 229-231, and 236-237
L21 Cancer I pp. 935-950
L22 Cancer II pp. 951-961, 965-970, and 884-885
L23 Stem cells and cloning pp. 899-909
E4 Exam IV (lectures 19-23)