Calendar and Readings

Suggested Textbooks

Buy at Amazon Hilts, Philip. Rx for Survival: Why We Must Rise to the Global Health Challenge. Penguin Books, 2007. ISBN: 9780143037989. [Preview with Google Books]

Buy at Amazon Skoog, Douglas A., F. James Holler, and Stanly R. Crouch. Principles of Instrumental Analysis. Cengage Learning, 2006. ISBN: 9780495012016.

Buy at Amazon Kucklick, Theodore R. The Medical Device R&D Handbook. CRC Press, 2012. ISBN: 9781439811894. [Preview with Google Books]

SES # LECTURES TOPICS LAB TOPICS READINGS
1 Introduction to Health and Wellness Fabrication Medical Fabrication Tools Tricorder X-Prize—Complete information about the competition, including guidelines, schedule, and requirements
2 Consumerization of Health Molecular Diagnostics  
3 Wetlab and Rapid Diagnostics Lateral Flow Immunoassys

Martinez, Andres W. "Three—dimensional Microfluidic Device Fabricated in Layered Paper and Tape." Proceedings of the National Academy of Sciences 105, no. 50 (2008): 19606–11.

Paper diagnostics Combur-10 test: Combur-Test® Product Line. Roche Diagnotics. Accessed December 20, 2010.

Grifantini, Kristina. "TR10: Paper Diagnostics." Technology Review, March/April 2009.

Urdea, Mickey, et al. "Requirements for High Impact Diagnostics in the Developing World." Nature 444 (2006): 73–9.

4 Low-cost Microfluidics Xurography and Legofluidics

Schilling, Eric, and Paul Yager. "Basic Microfluidic Concepts." September 7, 2001. Accessed August 25, 2009.

Goho, Alexandra. "Diagnosing the Developing World: Turning High Tech Innovations into Low—cost Medical Tests." Science News, February 14, 2004.

Sia, Samuel K., and Larry J. Kricka. "Microfluidics and Point- of-care Testing." Lab Chip 8 (2008): 1982–3.

5 Vital Signs Diagnostics Pulse Oximetry

Kahn, Jonathan. "Race in a Bottle." Scientific American, August 2007.

Wuethrich, Bernice, ed. "Introduction and Sustainable Use of Vaccines in Developing Countries." Proceedings of the Albert B. Sabin Vaccine Institute 12th Annual Vaccine Policy Colloquium, October 19–21, 2005.

"Students Devise Oral Quick- dissolve Strips for Rotavirus Vaccine." Johns Hopkins University Press Release, May 14, 2007.

Mullins, Justin. "Immune System in a Jar," New Scientist: Invention Blog, March 05, 2008.

Groleau, Rick. "Killer Disease on Campus: Making Vaccines." Public Broadcasting Service: NOVA, August,2002.

Mitragotri, Samir. "Immunization without Needles." Nature Reviews Immunology 5 (2005): 905–16.

Garcia-Contreras, Lucila, et al. "Immunization by a Bacterial Aerosol." Proceedings of the National Academy of Sciences 105, no. 12 (2008): 4656–60.

Flatow, Ira, and Alex Chadwick. "Vaccine Tech Could Help Millions in Developing Nations," National Public Radio, October 21, 2004.

6 Optics for Health Multispectral Imaging

Heraud, Phil, and Bayden Wood. "Editorial – The Latest Thinking and Developments in Optical Diagnosis." Analyst 138, no. 14 (2013): 3861–2.

7 Distributed Pathology Microscopy  
8 Midterm Presentations    
9 mHealth Strategies SmartPhone programming / App Inventor

You, David J., Tu San Park, et al. "Cell-phone-based Measurement of TSH Using Mie Scatter Optimized Lateral Flow Assays." Biosensors and Bioelectronics 40, no. 1 (2013): 180–5.

Martinez, Andres W., et al. "Simple Telemedicine for Developing Regions: Camera Phones and Paper-Based Microfluidic Devices for Real- Time, Off-Site Diagnosis." Analytical Chemistry 80, no. 10 (2008): 3699–707.

Szot, Agneiszka, et al. "Diagnostic Accuracy of Chest X- rays Acquired Using a Digital Camera for Low-cost Teleradiology." International Journal of Medical Informatics 73, no. 1 (2004): 65–73.

Amithap1982. "CytoSight a Telepathology Solution by KTwo Powered by Intel." Feb 4, 2009. YouTube. Accessed August 25, 2009. http://www.youtube.com/wat ch?v=ssp4cJyfOEU

10 Non-communicable Diseases Wearable Physiological Monitors I: Temperature, Respiration, GSR

Disease Control Priorities Project. Disease Control Priorities in Developing Countries [abstracts, PDF and full text HTML available for download]
- Chapter 30, "Diabetes: The Pandemic and Potential Solutions." by K. M. Venkat Narayan, et al.
- Chapter 33, "Cardiovascular Disease." by Thomas A. Gaziano, et al.

International Atomic Energy Agency. This resource may not render correctly in a screen reader.A Silent Crisis: Cancer Treatment in Developing Countries (PDF). September 2003.

McNeil Jr., Donald G. "In India, a Quest to Ease the Pain of the Dying," New York Times, September 11, 2007.

———. "Procedure May Save Women In Third World From Cancer," New York Times, March 25, 2003.

kwinoy. "ICT4D to Scale Cervical Cancer Prevention." May 07, 2008. YouTube. Accessed August 25,2009.
https://www.youtube.com/watch?v=RmqSnYyiA4E

11 Global Health Technology Design Wearable Physiological Monitoring II: Pulse Oximtery and Plethysmopgray

Hingson, Robert A. "The Development of the Hypospray for Parenteral Therapy by Jet Injection." Anesthesiology 10, no. 1 (1949): 66–75. [PDF available for download]

Towle, Richard L. "New Horizon in Mass Inoculation." Public Health Reports 75, no. 6 (1960): 471–6.

"Vaccination By Jet." The British Medical Journal 2, no. 5530 (1966): 1610.

Hernandez, Marita. "Hepatitis Cases Blamed on Clinic's Use of 'Jet Gun'," Los Angeles Times, October 8, 1985.

Anahtar, Melis N. "Needle-Free Injectors as a Sustainable Alternative to Syringes." MIT International Review, Spring 2008.

byronetics. "Aravind Eye Hospital." November 19, 2006. YouTube. Accessed August 25,2009.
https://www.youtube.com/watch?v=3cjnNPua7Ag.

12 Startup Guest Lectures    
13 Final Presentations    

Supplemental Readings

Supporting material for Rx for Survival

Geelhoed, Glenn W. This resource may not render correctly in a screen reader."Surgery and Healing in the Developing World." (PDF - 4.7MB) Landes Biosciences, 2005.

Buy at Amazon Werner, David, Carol Thurman, and Jane Maxwell. Where There Is No Doctor: A Village Health Care Handbook. Hesperian Foundation, 2013. ISBN: 9780942364156.

Buy at Amazon Gordon, Bruce, Richard Mackay, and Evan Rehfuess. Inheriting the World: The Atlas of Children's Health and the Environment. World Health Organization, 2004. ISBN: 9789241591560. [Preview with Google Books]

BIO Ventures for Global Health (BVGH). "Global Health Primer."–A tremendous resource on diseases that form the focus in global health: background information, descriptive "disease sheets", lists of organizations, NGOs, advocacy groups, biotech companies and other partnerships, all engaged in trying to address these problems.

Chowdury, Zafrin. "Bangladesh Launches Mass Immunization Campaign after Polio Re- emerges." UNICEF, 2006.

Google Flu Trends

Helft, Miguel. "Google Uses Searches to Track Flu's Spread." New York Times, November 11, 2008.

Medical Hacks: DIY projects with step by step instructions.